In Bangladesh, at present about 60 pharmaceutical companies are manufacturing 90 brands of Chlorpheniramine Maleate tablets. This project work has been designed to evaluate & report the quality & stability of some marketed Chlorpheniramine Maleate tablets available in Bangladesh. The selected brands were assayed spectrophotometrically and their physical parameters (weight variation, hardness, thickness, friability, disintegration time, and dissolution rate) were analyzed according to the official (BP/ USP) pharmacopial methods to evaluate their quality. The results showed that 7 brands of tablets meet the USP specification of potency and the remaining one brand was highly potent. All but one brands showed good results when they were tested for weight variation, thickness, disintegration time, It is evident from the study that most of the brand tested showed good result but few of them are substandard. So more steps and effective measures should be taken by the authority to ensure quality medicine.